Gale Encyclopedia of Genetic Disorders (2 Volume Set)

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Readable, well organized, and easy to use, this outstanding encyclopedia signifies a timely and major advance in providing in-depth and comprehensive coverage of medical genetics for the lay reader. The two volumes include nearly 400 substantive entries on genetic diseases and conditions as well as information on basic genetics concepts such as DNA, chromosomes, genetic testing, and pedigree analysis and construction (genetic family history). An advisory board of seven distinguished genetics specialists (clinical geneticists and genetic counselors) oversaw the accuracy of the text, which is authored by an international slate of clinicians, genetic counselors, and medical writers. Each of the alphabetically arranged entries follows a standard format definition, description, genetic profile, demographics, and signs and symptoms designed to answer the questions healthcare consumers actually ask. In addition, entries provide citations for further reading, contact information for support and advocacy organizations, and recommendations for notable web sites. Cross references for subjects without entries are interspersed throughout the work and are easy to follow. The key terms box that appears in select entries and provides succinct and understandable definitions is especially noteworthy. Other special features include a comprehensive glossary, a chromosome map, a guide to symbols for pedigree charts, and an organizations directory all features that should make understanding difficult genetics concepts much easier. The Encyclopedia of Genetic Disorders and Birth Defects (Facts On File, 2000. 2d ed.) has long been the authoritative title for this subject and should remain on the shelf. However, larger consumer health collections and those that frequently receive requests for consumer information on clinical genetics are advised to purchase this as a supplement; it is worth every penny. Highly recommended. Gail Hendler, New York University Sch. of Medicine



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Oxford Dictionary of Biochemistry and Molecular Biology

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From Booklist

Just as its title suggests, this work is a dictionary of more than 17,000 terms currently in use in the fields of biochemistry and molecular biology. Entries are uniformly concise, with entries for the most complex topics (such as protein) covering only about half a page. In a single alphabet, the dictionary includes topics and methods, chemical substances, and brief biographical entries of key scientists. The only illustrations are structure diagrams of the more complex chemical compounds. Appendixes help the reader understand scientific nomenclature and Greek symbols, list organizations and Web sites of interest in the field, and cover current hot topics in biochemistry. Despite its low price (especially for a science reference source), this dictionary is not for every library. Because it will require a significant scientific background to be able to understand the content of this work, it is beyond the reach of the casual reader. Libraries supporting research or college-level study in the field will find it useful, but other libraries will be able to rely on existing chemical and biological reference works to cover this material. For public libraries, the eighth edition of the McGraw Hill Encyclopedia of Science and Technology [RBB S 15 97] and The Merck Index (12th ed., Merck, 1996), which is an excellent source for information on chemical compounds, will fill most needs. --This text refers to an out of print or unavailable edition of this title.

Review

' A volume like this in a research lab really is likely to prove its worth' Reference Reviews

" ... it is very good, comprehensive, impressive (used on several occasions), and worth the money" Cell Biology International

" ... a very useful expanatory dictionary for students, scientists, and university and laboratory libraries ... " Photosynthetica


# 753 pages
# Publisher: Oxford University Press, USA; Revised edition (February 24, 2000)
# Language: English
# ISBN-10: 0198506732
# ISBN-13: 978-0198506737



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The Biochemistry of Cell Signalling



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The Biochemistry of Cell Signalling
by E. J. M. Helmreich

ISBN-10 / ASIN: 0198508204
ISBN-13 / EAN: 9780198508205
Publisher: Oxford University Press, USA
Number Of Pages: 368
Publication Date: 2001-09-13


The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. The design of signalling cascades is explained by describing central signalling pathways: the Ras-regulated MAPK and PI-3 pathways; the Rho/Rac/Cdc 42 pathway controlling chemotaxis and regulating the cytoskeleton; the G protein coupled receptor cascades in response to sensory and hormonal signals; signalling by TGF-ss in morphogenesis; cytokine signalling that controls haemopoiesis. There is also a discussion of the insulin response. As phosphorylation - dephosphorylation is involved in nearly all cellular regulatory processes, Part 1 concludes with a synopsis of its role in signalling. Part 2 describes the implementation of the signalling cascades focusing on the effect on gene transcription. After a brief description of the transcriptional machinery the regulation of transcription by cytokines and growth factors in the control of cell growth and the mechanisms and sites of control are discussed in detail. The regulators discussed include Jun/Fos, NF-AT, SREBPs, and STATs. The next two chapters cover gene regulation by nuclear receptors, including both the steroid hormone receptors and non-steroid nuclear receptors e.g. the retinoic acid receptors RAR and RXR. Part 3 studies the global cellular regulatory programs for the control of cell growth and proliferation. The first chapter concerns the regulation of the cell cycle and the role of the cyclin-dependent kinases, telomerase, Ran, and cell cycle checkpoints. The next topic is the signalling pathways in apoptosis: the TNF-receptor family death receptors, caspases, and the intracellular apoptosis signals and the role of apoptosis in the lifecycle of cells. Part 3 ends with a discussion of the signal pathways involved in the immune response, focusing on the involvement of cell-cell interactions. Part 4 considers loss of regulatory control and its consequences with respect to the molecular basis of cancer. It first describes the cellular regulatory proteins that have oncogenic potential, how they can become oncogenic and cause the transformation of normal cells to cancerous cells. Next is an analysis of the loss of developmental controls, the APC protein, ss-catenin, and the Wnt pathway, that lead to mature terminally differentiated cells reverting to immature embryonic cells. The book ends with a summary of the molecular and cellular causes of cancer and an outlook for novel therapies. Throughout the text, the emphasis is on structure and mechanism and is well illustrated with 200 figures. The Biochemistry of Cell Signalling will be an invaluable companion to all graduate students studying cell signalling.

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Biochemistry of signal transduction and regulation 3d ed










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Handbook of Food Science, Technology, and Engineering - 4 Volume Set (Food Science and Technology)



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Handbook of Food Science, Technology, and Engineering - 4 Volume Set (Food Science and Technology)
By: Y.H. Hui, Frank Sherkat
Publisher: CRC
Number Of Pages: 3632
Publication Date: 2005-12-19
ISBN-10 / ASIN: 0849398479 ISBN-13 / EAN: 9780849398476
Binding: Hardcover

Filling a gap in the literature in this area, this four-volume set explores scientific data of immense complication and complexity. The combined effort of more than 150 professionals from more than 15 countries and backgrounds, the book is an essential reference on food science for professionals in the government, industry, and academia. Volume I covers properties, products, analysis, and microbiology. Volume II explores attributes, fermentation, safety, ingredients, and nutrition. Volume III discusses food engineering and processing and Volume IV food technology and processing. Unique in both depth and breadth, each volume contains about 1000 pages of scientific and technical data.


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File size : 30 MB

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Bioinformatics Algorithms - Techniques and Applications

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Bioinformatics Algorithms: Techniques and Applications
Language: English | 500 pages | Data: 2008 | PDF | size : 6 Mb


Targets the future collaboration of researchers in algorithms, bioinformatics, and molecular biology. It addresses critical bioinformatics research areas of protein-protein interaction, molecular modeling in drug design, and structural biology. Some of the most important topics in the field of bioinformatics are covered with selected topics that are gaining increased interest, including drug design, gene finding, and text mining in bioinformatics.

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Structure Of 'Beneficial' Virus That Can Infect Cancer Cells

Structure Of 'Beneficial' Virus That Can Infect Cancer Cells Solved



A research team has solved the 3-D structure of Seneca Valley Virus-001. (Credit: Image courtesy of Scripps Research Institute)


ScienceDaily (Oct. 9, 2008) — The 3-D structure of the virus, known as Seneca Valley Virus-001, reveals that it is unlike any other known member of the Picornaviridae viral family, and confirms its recent designation as a separate genus "Senecavirus." The new study reveals that the virus's outer protein shell looks like a craggy golf ball — one with uneven divets and raised spikes — and the RNA strand beneath it is arranged in a round mesh rather like a whiffleball.

"It is not at all like other known picornaviruses that we are familiar with, including poliovirus and rhinoviruses, which cause the common cold," says the study's senior author, Associate Professor Vijay S. Reddy, Ph.D., of The Scripps Research Institute. "This crystal structure will now help us understand how Senecavirus works, and how we can take advantage of it."

The Senecavirus is a "new" virus, discovered several years ago by Neotropix Inc., a biotech company in Malvern, Pennsylvania. It was at first thought to be a laboratory contaminant, but researchers found it was a pathogen, now believed to originate from cows or pigs. Further investigation found that the virus was harmless to normal human cells, but could infect certain solid tumors, such as small cell lung cancer, the most common form of lung cancer.

Scientists at Neotrophix say that, in laboratory and animal studies, the virus demonstrates cancer-killing specificity that is 10,000 times higher than that seen in traditional chemotherapeutics, with no overt toxicity. The company has developed the "oncolytic" virus as an anti-cancer agent and is already conducting early phase clinical trials in patients with lung cancer.

But the researchers still did not know how the virus worked, so they turned to Reddy. He and his Scripps Research team, especially Sangita Venkataraman, Ph.D., a postdoctoral researcher, determined the Senecavirus crystal structure.

Reddy describes the differences they found between other picornaviruses and the Senecavirus as like variations among car models of the same manufacturer. "The chassis is the same, but the body style is different," he says. "How the body of a virus is shaped determines how it infects cells."

The structure of the Senecavirus is also depicted at http://viperdb.scripps.edu/, the "Virus Particle Explorer" developed at Scripps Research by Reddy and his colleagues. The online database is a worldwide resource for information on the structure of viral particles; it contains details of 253 viruses to date.

Once the structure of Seneca Valley Virus-001 was solved, researchers went on to identify several areas on the viral protein coat that they think might hook onto receptors on cancer cells in the process of infecting them. The researchers are now conducting further investigations on this process. "It will be critically important to find out what region of its structure the virus is using to bind to tumor cells, and what those cancer cell receptors are," Reddy says. "Then we can, hopefully, improve Senecavirus enough to become a potent agent that can be used with many different cancers."

The research was supported by grants from the National Institutes of Health.


Journal reference:

  1. S. Venkataraman, V. Reddy, Seshidhar P. Reddy, Neeraja Idamakanti, Paul L. Hallenbeck and Jackie Loo. Structure of Seneca Valley Virus-001, an oncolytic picornavirus representing a new genus. Structure, Vol 16, 1555-1561, 08 October 2008 [link]
Adapted from materials provided by Scripps Research Institute.

an article form sciencedaily.com

How Infectious Bacteria Can Switch Species

Researchers Discover How Infectious Bacteria Can Switch Species

ScienceDaily (Oct. 9, 2008) — Scientists from the Universities of Bath and Exeter have developed a rapid new way of checking for toxic genes in disease-causing bacteria which infect insects and humans. Their findings could in the future lead to new vaccines and anti-bacterial drugs.


They studied a bacterium called Photorhabdus asymbiotica, which normally infects and kills insects, but which can also cause an unpleasant infection in humans.

By testing groups of genes from the bacteria against three types of invertebrates (insects, worms and amoebae) and mammalian cells, the scientists were able to identify toxins and other molecules, called virulence factors, made by the bacteria that allow it to infect each type of organism.

By pinning down the genes responsible for each of these possible virulence factors and comparing them with the genes of well known bacteria, the scientists have been able to map out which regions of the bacteria’s DNA control its ability to infect and damage invertebrates, and also potentially humans.

The researchers from Bath and Exeter are publishing their findings in the prestigious journal Proceedings of the National Academy of Sciences of the United States of America.

Dr Nick Waterfield from the University of Bath’s Department of Biology & Biochemistry said: “Many bacteria have evolved to infect one particular type of plant or animal and most of the toxins they use to do this also have an effect in other hosts.

“Some of the toxins they use for infecting can also allow the bacteria to jump across into another species like humans, perhaps with fatal consequences.”

Dr Maria Sanchez-Contreras, who works with Dr Waterfield at the University of Bath said: “We have developed a new way of discovering a greater number of previously unknown toxins and measuring how dangerous or virulent these bacteria are. Identifying the genes responsible for the production and secretion of these bacterial toxins will allow us find ways to prevent disease.

“Our new technique, called Rapid Virulence Annotation (RVA), allows us to make faster assessments of the disease-causing agents in multiple types of organism; it lets us pinpoint sequences of genes which may pose a risk to humans; and it gives us a powerful tool to identify virulence genes in other known bacteria.

“Finally, it helps us identify new targets for drugs to fight these diseases and control pests, and for developing preventive vaccines.”

Richard ffrench-Constant, Professor of insect microbiology from the University of Exeter’s Cornwall Campus adds: “RVA allows us to look for virulence factors that are totally novel and does not rely upon traditional searches based on factors already known from other bacteria. We have already discovered that some totally unexpected genes are indeed involved in bacterial virulence. This technique should prove to be a gold mine for potential vaccine candidates.”

The scientists are already using this relatively cheap and highly accurate RVA technique in other disease-causing bacteria to identify the genes which allow some diseases to jump the species barrier.


Journal reference:

  1. Waterfield et al. Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome library and multiple invertebrate hosts. Proceedings of the National Academy of Sciences, 2008; DOI: 10.1073/pnas.0711114105
Adapted from materials provided by University of Bath.


Dr Nick Waterfield and Dr Maria Sanchez-Contreras are investigating bacteria that infect the Tobacco Hawk Moth caterpillar. (Credit: Image courtesy of University of Bath)

an article from sciencedaily.com

Java for Bioinformatics and Biomedical Applications



Springer.Java.for.Bioinformatics.and.Biomedical.Applications.Dec.2006.READ.NFO.eBook-BBL

TITLE : Java for Bioinformatics and Biomedical Applications (Hardcover)
AUTHOR : by Harshawardhan Bal (Author), Johnny Hujol (Author)
PUBLISHER : Springer publisher
ISBN : 0387372350
EDITION : 1st
PUB DATE : December 01, 2006
LANGUAGE : English
FORMAT : PDF
SIZE : 05 x 2.88 MB





Quote:
[ R e l e a s e N o t e s ]

This book aims to combine industry standard software engineering and
design principles, genomics and bioinformatics and cancer research. It
focuses on creating and integrating practical, useful tools for the
scientific community in the context of real-life, real-value biomedical
problems that researchers face on a routine basis, rather than being
just a didactic exercise in learning a programming platform. The book
leverages technologies for molecular biology, genomics and
bioinformatics and cancer research developed by the NIH, NCI-Center for
Bioinformatics (NCICB), the National Center for Biotechnology
Information (NCBI, a division of the National Library of Medicine (NLM)
at the NIH) and Stanford University.

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Virus Structure and Assembly (Advances in Virus Research)

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* Publisher: Academic Press
* Number Of Pages: 448
* Publication Date: 2005-06-23
* Sales Rank: 1940497
* ISBN / ASIN: 012039863X
* EAN: 9780120398638
* Binding: Hardcover
* Manufacturer: Academic Press
* Studio: Academic Press

Book Description:

Written by experts in their field, Virus Structure and Assembly summarizes our current state of

knowledge in the field of virus structure and assembly, comparing and contrasting the mechanisms

adopted by viruses with a wide diversity of genome and host. It will serve as an invaluable

reference for researchers in virology, microbiology, epidemiology, molecular biology, and public

health.

* Witness to the remarkable advancement in the field of virus structure and assembly
* A unique opportunity to compare and contrast mechanisms adopted by a diverse range of viruses

from bacteriophages and RNA viruses to Bluetongue, Influenza and Hepatitis B
* Numerous illustrations including color
* Discussion on the VIPER database, a repository for all high-resolution structures of simple

icosahedral viruses, and on application of mass spectrometry to the analysis of structures

present in biological specimens, such as HIV-1

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World of Microbiology and Immunology by K. Lee Lerner

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World of Microbiology and Immunology
by K. Lee Lerner

ISBN-10 / ASIN: 0787665401
ISBN-13 / EAN: 9780787665401
Publisher: Gale Cengage
Number Of Pages: 699
Publication Date: 2002-11


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Infectious Disease

Book Description

A clinical focus, reader-friendly format, and international scope make this landmark, two-volume reference unique among encyclopedic infectious disease resources. More than 300 worldwide experts cover all aspects of the investigation, diagnosis, and clinical management of every infectious condition. Abundant "Practice Points" convey valuable clinical pearls from the authors. The comprehensively updated 2nd Edition features an even more geographically diverse set of contributors than its predecessor, as well as brand-new information on nosocomial infections, HIV/AIDS, and many other timely topics.

About the Author
Jonathan Cohen, Chairman, Department of Infectious Diseases and Microbiology, Imperial College School of Medicine; Honorary Consultant Physician, Hammersmith Hospital, London, UK; and William G Powderly, MD, Professor of Medicine, Co-Director, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO

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Molecular biology of the cell

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Molecular Biology of the Cell, 4th Edition,
ISBN-10: 0815332181
ISBN-13: 9780815332183
List Price: $105.00 (from now free)


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Cell & Molecular Biology

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Cell & Molecular Biology

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[chemical] Biotechnology- EPST

Encyclopedia of Physical Science and Technology


Biotechnology

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Putting Biotechnology to Work: Bioprocess Engineering

Putting Biotechnology to Work: Bioprocess Engineering
Author: National Research Council
ISBN: 0309047854
Publisher: National Academies Press
Publication Date: 1992-11
Number Of Pages: 132
pdf, 1,6 mb


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Biotechnology is broadly defined in a 1991 Office of Technology
Assessment report as "any technique that uses living organisms (or parts of
organisms) to make or modify products, to improve plants or animals, or to
develop microorganisms for specific uses." This technology has been
instrumental in the development and implementation of processes for the
manufacture of antibiotics and other pharmaceuticals, industrial sugars, alcohols,
amino acids and other organic acids, foods, and specialty products through the
application of microbiology, fermentation, enzymes, and separation technology.
Engineers, working with life scientists, often achieved scale-up to industrial
production in remarkably short periods. A relatively small number helped to
catalyze, over a period of 50 years, the growth of the pharmaceutical, food,
agricultural-processing, and specialty-product sectors of the U.S. economy to the
point where sales now exceed $100 billion/year.

Aquaculture and Fisheries Biotechnology: Genetic Approaches

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Rex A. Dunham
Aquaculture and Fisheries Biotechnology: Genetic Approaches
CABI Publishing | ISBN: 0851995969 | 2004 | 384 pages | PDF | 3.7 MB


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The genetic improvement of fish for aquaculture and related fisheries is a field of research that has seen immense advances in recent years. Yet there is no book which provides an accessible overview of the subject. This book aims to fill this gap and will be suitable for advanced students and researchers in animal genetics, fish biology and aquaculture.


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Basic Concepts in Biochemistry: A Student's Survival Guide

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Book Description
This second edition continues to innovatively review the toughest concepts in biochemistry for maximum comprehension in a short period of time. Unlike conventional texts or review books that stress memorizing facts, BASIC CONCEPTS stresses the mastering of fundamental concepts, so that the reader truly comprehends the material and feels comfortable applying it. Dr. Gilbert uses simple, jargon-free language and award-winning teaching techniques including algorithms, mnemonics and clinical examples.

Book Info
Baylor College of Medicine, Houston, TX. Practical study guide to biochemistry for first- and second-year medical students. Explains basic concepts in detail using simple language. Includes two new chapters: one outlines the concepts of membranes and membrane proteins, and the other focuses on signal transduction pathways. Previous edition: c1992. Softcover.


# 331 pages
# Publisher: McGraw-Hill Medical; 2 edition (November 16, 1999)
# Language: English
# ISBN-10: 0071356576
# ISBN-13: 978-0071356572

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Color Atlas Of Biochemistry

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Book Description
This Thieme Flexibook presents the fundamentals of human and mammalian biochemistry in 192 stunning color plates. Key features include the unique combination of highly effective color graphics and comprehensive figure legends. Unified color-coding of atoms, coenzymes, chemical classes, and cell organelles allows quick recognition of all involved systems, and computer graphics provide simulated 3D representation of many important molecules. This Flexibook is ideal for students of all levels with its complete coverage of the structure and composition of biologically relevant molecules and their metabolism.


# 467 pages
# Publisher: Thieme Medical Publishers; 2 Rev Enl edition (December 2004)
# Language: English
# ISBN-10: 1588902471
# ISBN-13: 978-1588902474


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Marks Basic Medical Biochemistry* A Clinical Approach

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Book Description
This best-selling resource utilizes a comprehensive yet practical approach that students understand. The authors present facts and pathways to emphasize how the underlying biochemistry is related to the body's overall physiological functions. Detailed case studies show students the relationship between biochemistry and clinical problems. The Second Edition has been heavily revised with completely updated illustrations while maintaining the unique, patient-oriented approach that made the original so popular.


# 900 pages
# Publisher: Lippincott Williams & Wilkins; 2 edition (August 1, 2004)
# Language: English
# ISBN-10: 0781721458
# ISBN-13: 978-0781721455


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Flavonoids: Chemistry, Biochemistry and Applications

Review

the latest in a series of what are widely considered as flavonoid 'bibles' a must-have source of reference material for anyone actively researching or interested in flavonoids I found [it] both useful in my capacity as a scientist actively researching in this field, and would recommend the book to those in a similar situation. It should also be of interest to certain universities that teach courses related to plant secondary products.
-Paul A. Kroon, Chemistry World, May 2007
As interest in the impact and health benefits of flavonoids continues to grow, this book reflects the dedicated commitment of flavonoid researchers to the improvement of human health and provides the most comprehensive, up-to-date source of information on all known flavonoids.
-Anticancer Research, 2006

I consider this book a highly valuable source of material considering not just the actual text but also the references cite.
-La Revista Italiana Delle Sostanze Grasse, 2006
remarkable piece of work! not only a valuable compilation of advances and perspectives in the field of flavonoid chemistry and biochemistry, but should also serve as a useful handbook for both research and testing in the field. Personally, I have already placed this heavyweight volume on my shelf of must-have books on polyphenol-oriented research.
-Stéphane Quideau, Angewandte Chemie International Edition, 2006

This excellent and timely volume on flavonoids provides a comprehensive update to the last compendium on the subjecthighly recommended to anyone interested in studying flavonoids from chemical, biochemical, pharmaceutical, nutraceutical, taxonomic, and economic points of view.
-Rachel Mata, Journal of Natural Products, 2007

Since 1994, remarkable progress has been made in our understanding of flavonoid biosynthesis. DNA sequences are now available for most of the enzymes required to form the common flavonoid types. Biotechnology of the flavonoid pathway was in its infancy at the start of the 1990s, but is currently being widely applied to develop improved cultivars of ornamental, pasture, and food crops. As knowledge of flavonoids and human health progresses, one may anticipate that gene technology will be increasingly applied to improve the health characteristics of crop plants.
- Prof. Øyvind M. Andersen

Book Description
Advances in the flavonoid field have been nothing short of spectacular over the last 20 years. While the medical field has noticed flavonoids for their potential antioxidant, anticancer and cardioprotectant characteristics, growers and processors in plant sciences have utilized flavonoid biosynthesis and the genetic manipulation of the flavonoid pathway in plants to improve the nutritional and ornamental value of crops. Flavonoids: Chemistry, Biochemistry and Applications covers each class of flavonoid and presents the historic advances made in flavonoid research since the 1994 publication of an earlier text, Flavonoids Advances in Research Since 1986. This book details the analytical techniques scientists have used to achieve an improved understanding of flavonoid structures and functions as well as advances in the genetic manipulation of the flavonoid pathway, and the discovery of many new flavonoids. It indicates which techniques are best suited for the isolation and structure determination of flavonoids and whether the structures are novel. While explaining how to evaluate the flavonoid content in food and beverages, the book reveals the biotechnological advances that have allowed nutritionists and plant physiologists to assess the possible effects of flavonoids. As interest regarding the impact and health benefits of flavonoids continues to grow, Flavonoids: Chemistry, Biochemistry and Applications reflects the continuing commitment of flavonoid researchers to the improvement of human health and provides the most comprehensive, up-to-date source of information for all known flavonoids.


# 1256 pages
# Publisher: CRC; 1 edition (December 9, 2005)
# Language: English
# ISBN-10: 0849320216
# ISBN-13: 978-0849320217


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Inorganic Biochemistry of Iron Metabolism



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Book Description

Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism.

The first edition of this book was published in 1991 and since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature that has led to the need for this second edition.

This collaboration between five specialist authors covers the fundamental concepts and applied aspects of iron biochemistry. Completely updated it reflects the latest advances in the field and now includes new chapters on iron and cell division and the interactions of iron with other metals.

Exploring the chemistry, biology, biochemistry, physiology and medical aspects of iron in biological systems from microorganisms to man this essential title:
* Introduces illustrations and colour photos to make the basic concepts far clearer
* Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc
* Provides additional anecdotes
* Incorporates an extensive and up-to-date bibliography
* Covers both fundamental and applied aspects

Inorganic Biochemistry of Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 2nd Edition is therefore essential to researchers interested in iron in the areas of:
Biochemistry
Molecular Biology
Microbiology
Cell Biology
Nutrition and Medical Sciences

University lecturers of:

Bioinorganic Chemistry
Inorganic Chemists interested in Biochemistry
Biochemists with an interest in iron metabolism

Health professionals with an interest in iron metabolism diseases

Pharmacologists in drug companies interested in developing novel iron binding drugs


# 358 pages
# Publisher: Wiley; 2 edition (October 15, 2001)
# Language: English
# ISBN-10: 047149223X
# ISBN-13: 978-0471492238


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Analytical Biochemistry 3rd Edition

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Book Description

Now an established handbook of principles and techniques, this text develops an understanding of the relevance of four fundamental properties of the analyte: shape, polarity, charge and size, to the three key types of analysis: separation, identification and quantification. The third edition of Analytical Biochemistry has now been fully updated in content and format, making it even more accessible to students learning how to select analytical techniques and recognise their scope and limitations.


# 504 pages
# Publisher: Prentice Hall; 3 edition (January 10, 1998)
# Language: English
# ISBN-10: 058229438X
# ISBN-13: 978-0582294387


Code:

http://rapidshare.com/files/76403135/Analytical_Biochemistry_3rd_ed_-_David_Holme__Hazel_Peck.pdf

Toxicological Chemistry and Biochemistry

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Book Description
This unique book bridges the gap between toxicology and chemistry at a level understandable by a wide spectrum of readers with various interests and a broad range of backgrounds in chemistry, biochemistry, and toxicology. The third edition has been thoroughly updated and expanded to reflect recent advances in important areas of research, including toxicogenetics and toxic effects on various body systems. Toxicological Chemistry and Biochemistry, Third Edition begins by outlining the basic concepts of general chemistry, organic chemistry, and biochemistry needed to understand the topics in the book. The author then presents an overview of environmental chemistry so that you can understand the remainder of the material covered within that framework. He also discusses biodegradation, bioaccumulation, and biochemical processes that occur in water and soil. The new chapter on toxic effects considers toxicities to the endocrine and reproductive systems, and the section on xenobiotics analysis deals with the determination of toxicants and their metabolites in blood and other biological materials. The chapter on the genetic aspects of toxicology discusses the ways in which chemical damage to DNA can cause mutations, cancer, and other toxic effects on specific body systems, and it considers the role of genetics in determining individual susceptibilities to various toxicants. Toxicological Chemistry and Biochemistry, Third Edition retains the basic information and structure that made the first two editions popular with students and industry professionals, while enhancing the usefulness of the book and modernizing it in important areas. Review questions and supplementary references at the end of each chapter round out the third edition of this bestselling work.


# 425 pages
# Publisher: CRC; 3 edition (September 25, 2002)
# Language: English
# ISBN-10: 1566706181
# ISBN-13: 978-1566706186


Code:
http://rapidshare.com/files/76432195/Tox_Chem.pdf

Biochemistry and Genetics:PreTest Self-Assessment and Review

Book Description

PreTest is the medical student’s most dynamic weapon for acing the USMLE Step 1.

Great for course review and exams, too! Biochemistry & Genetics PreTest asks the right questions so you’ll know the right answers. Open it and start learning what’s on the test.

PreTest is the closest thing you can get to seeing the test before you take it.

This one-of-a-kind test prep guide helps you to:
*Get to know material on course exams and the USMLE Step 1
*Practice with 500 clinically-oriented multiple-choice questions
*Review key facts for exam success
*Build confidence, skills, and knowledge

There are plenty of answers out there. But only PreTest delivers the right questions.

From the Back Cover
PreTest is the medical student’s most dynamic weapon for acing the USMLE Step 1.

Great for course review and exams, too! Biochemistry & Genetics PreTest asks the right questions so you’ll know the right answers. Open it and start learning what’s on the test.

PreTest is the closest thing you can get to seeing the test before you take it.

This one-of-a-kind test prep guide helps you to:
*Get to know material on course exams and the USMLE Step 1
*Practice with 500 clinically-oriented multiple-choice questions
*Review key facts for exam success
*Build confidence, skills, and knowledge


Code:

http://rapidshare.com/files/28186444/Biochemistry.rar

Lehninger Principles of Biochemistry, Fourth Edition

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Lehninger Principles of Biochemistry, Fourth Edition brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications.

Quote:
Before I say anything about this book, I offer for your consideration the fact that I am not a student of biochemistry; I am a physics graduate student. My desire to learn about biochemistry had nothing to do with receiving any sort of degree. Then consider the fact that this is the only Amazon.com review I have ever written. These facts alone should tell you that I must have found this book pretty remarkable.
This text was required for all three of the biochemistry classes I took as an undergraduate student, and it never let me down. It contains a positively HUGE amount of information, which Nelson and Cox have somehow managed to digest and present for the layperson in a way that is both engaging and understandable. The writing style is superb, and the visual aids are numerous and of exceptionally high quality.
How many times while cramming for the next day's test at 3:00 am have you caught yourself reading material that isn't even covered on the exam, just because it's interesting? It happened to me. And while I will admit to having some pretty nerdy tendencies some times, I don't think I'm quite that abnormal.
Don't listen to the reviewers who say they wish this book went into more depth on some issues, because they should know better. I can assure you that there is no lack of depth here. This is an introductory text. You read it if you want an introduction. If the nitty-gritty were found in introductory texts, there would be no need for advanced texts, now would there?

Coming from a great lover of textbooks, I'll put it to you plainly and simply: Among my top 5 favorite textbooks, this is the only one that isn't about physics. If you are looking for an introductory biochemistry texbook, then I don't believe you can go wrong with this one.


# 1100 pages
# Publisher: W. H. Freeman; 4 edition (April 23, 2004)
# Language: English
# ISBN-10: 0716743396
# ISBN-13: 978-0716743392


Code:
http://rapidshare.com/files/88735811/Lehnin.pdf

Lehninger Principles of Biochemistry, Fourth Edition

Image

Lehninger Principles of Biochemistry, Fourth Edition brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications.

Quote:
Before I say anything about this book, I offer for your consideration the fact that I am not a student of biochemistry; I am a physics graduate student. My desire to learn about biochemistry had nothing to do with receiving any sort of degree. Then consider the fact that this is the only Amazon.com review I have ever written. These facts alone should tell you that I must have found this book pretty remarkable.
This text was required for all three of the biochemistry classes I took as an undergraduate student, and it never let me down. It contains a positively HUGE amount of information, which Nelson and Cox have somehow managed to digest and present for the layperson in a way that is both engaging and understandable. The writing style is superb, and the visual aids are numerous and of exceptionally high quality.
How many times while cramming for the next day's test at 3:00 am have you caught yourself reading material that isn't even covered on the exam, just because it's interesting? It happened to me. And while I will admit to having some pretty nerdy tendencies some times, I don't think I'm quite that abnormal.
Don't listen to the reviewers who say they wish this book went into more depth on some issues, because they should know better. I can assure you that there is no lack of depth here. This is an introductory text. You read it if you want an introduction. If the nitty-gritty were found in introductory texts, there would be no need for advanced texts, now would there?

Coming from a great lover of textbooks, I'll put it to you plainly and simply: Among my top 5 favorite textbooks, this is the only one that isn't about physics. If you are looking for an introductory biochemistry texbook, then I don't believe you can go wrong with this one.


# 1100 pages
# Publisher: W. H. Freeman; 4 edition (April 23, 2004)
# Language: English
# ISBN-10: 0716743396
# ISBN-13: 978-0716743392

Code:
http://rapidshare.com/files/88735811/Lehnin.pdf

Modified Nucleosides: in Biochemistry, Biotechnology and Medicine (free)

Modified Nucleosides: in Biochemistry, Biotechnology and Medicine (US$440)

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Modified Nucleosides: in Biochemistry, Biotechnology and Medicine
By Piet Herdewijn

* Publisher: Wiley-VCH
* Number Of Pages: 684
* Publication Date: 2008-10-13
* ISBN-10 / ASIN: 3527318208
* ISBN-13 / EAN: 9783527318209
* Binding: Hardcover

Product Description:

Edited by one of the main driving forces behind the field's momentous rise in recent years, this one-stop reference is the first comprehensive resource to integrate recent advances.
The first part addresses biochemical aspects and applications, the second and third parts are devoted to compounds with therapeutic potential, with the third part focusing on newly introduced anticancer nucleoside drugs.
Essential reading for every scientist working in this area.

Download:

Code:

http://rapidshare.com/files/143122337/ModiNucleosidesBioNMed.rar

or

http://www.megaupload.com/?d=1FJX8LDN

Sherris Medical Microbiology

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Review
Doody's : "The first 58 chapters summarize the epidemiology, pathogenesis, manifestations, diagnosis, treatment, and prevention (if indicated) of the major bacterial, viral, fungal and parasitic disease entities. The remaining 14 chapters cover infectious diseases. I like the way important points are emphasized in red script at the edges of each page. The book is very user-friendly with its icons of organism, disease, and clinical aspects. The book may be less detailed in the arena of infectious diseases." "This is a very useful resource for students of basic medical science to use to help in synthesizing material with clinical information. The basic knowledge of bacteria, viruses, etc., should stimulate the intellectual curiosity of students to apply their knowledge in the clinical arena. The updated edition is certainly justified."

Book Description
The leading microbiology text! Thoroughly revised and updated, this book provides students with a solid grasp of etiologic agents, pathogenic processes, epidemiology, and the basis of major therapy. Includes complete discussions of the major bacterial, viral, fungal, and parasitic pathogens. Highlighted marginal notes and clinical applications are included throughout.

See all Editorial Reviews
Product Details

* Hardcover: 992 pages
* Publisher: McGraw-Hill Medical; 4 edition (July 14, 2003)
* Language: English
* ISBN-10: 0838585299
* ISBN-13: 978-0838585290


Code:

http://rapidshare.com/files/95884909/Siology_-_As.pdf

World's #1 Academic outline - Microbiology

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Introduction, Hystory of Microbiology, Organismal Evolution, The Cell Theory, How Prokaryotes and Eukaryotes Differ, Koch's Postulates, Food Borne Pathogens, Genetics, Metabolism, Microbial Differentation, Microscopes, Types of Microbial Yhe Genetic Code, Metabolism, Microbes Used In Foods, Oxigen Use, Reproduction of Fungi, The Immune System, Photosyntes, Fermentation, Medical Mycology... and others.

Download here:

Code:

http://rapidshare.com/files/72185866/biology.rar

Freshwater Microbiology

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Download Description
This unique textbook takes a broad look at the rapidly expanding field of freshwater microbiology. Concentrating on the interactions between viruses, bacteria, algae, fungi and micro-invertebrates, the book gives a wide biological appeal. Alongside conventional aspects such as phytoplankton characterisation, seasonal changes and nutrient cycles, the title focuses on the dynamic and applied aspects that are not covered within the current textbooks in the field. Complete coverage of all fresh water biota from viruses to invertebrates Unique focus on microbial interactions including coverage of biofilms, important communities on all exposed rivers and lakes. New information on molecular and microscopical techniques including a study of gene exchange between bacteria in the freshwater environment. Unique emphasis on the applied aspects of freshwater microbiology with particular emphasis on biodegradation and the causes and remediation of eutrophication and algal blooms.


Code:

http://rapidshare.com/files/76296129/Water_Fresh.pdf

Colour Atas of Microbiology





Code:
http://rapidshare.com/files/39149350/microb.rar

The Desk Encyclopedia of Microbiology



























Review
"This is a useful reference...I recommend this volume for any academic college or university library."
-E-STREAMS, Paula J. Wolfe, University of Arizona Library, U.S. (October 2004)

"...no longer need we hear the refrain: if only there was an easy to understand, readily available, single source."
- Henry D. Isenberg, Long Island Jewish Medical Center, N.Y. (November 2004)

"...well written and authoritative."
-Microbiology Today (November 2004)

"This work provides a compact, affordable overview of microbiology topics that are of widest interest in the field."
-S.K. Oelker, Drew University, U.S., (November 2004)


# 1166 pages
# Publisher: Academic Press; 1 edition (July 2003)
# Language: English
# ISBN-10: 0126213615
# ISBN-13: 978-0126213614


Code:
http://rapidshare.com/files/74797559/Micro_Desk.pdf

JAWETZ, MELNICK and ADELBERG'S MEDICAL MICROBIOLOGY 24th

Jawetz, Melnick, & Adelberg's Medical Microbiology (LANGE Series) - 24th Edition




















Author: Geo. F. Brooks
Book Description

The landmark clinical guide to the role microorganisms play in human health and illnesses -extensively revised and updated

Linking fundamental microbiology concepts with the diagnosis and treatment of clinical infections, this one-of-a-kind, portable text delivers an essential overview of the organisms and agents involved in clinical microbiology. In addition to brief descriptions of the organisms, you'll find vital perspectives on pathogenesis, diagnostic laboratory tests, clinical findings, treatment, and epidemiology. The book's purpose is to introduce basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology giving you a far-reaching, yet accessible review of the discipline that you can't find anywhere else. Supporting this acclaimed coverage are more than 300 informative illustrations and tables, each designed to clarify and drive home important chapter concepts.

New to this Edition:

* Updates to critical topics throughout, particularly in the areas of hepatitis viruses, the HIV virus, and bacterial virulence factors
* Refreshed USMLE questions
* Revised list of microorganisms and viruses featured on the inside of the book's covers

Product Details

* Paperback: 832 pages
* Publisher: McGraw-Hill Medical; 24 edition (April 20, 2007)
* Language: English
* ISBN-10: 0071476660
* ISBN-13: 978-0071476669
* Product Dimensions: 9 x 7.3 x 1.2 inches

Format: CHM

LINK -

Code:

http://rapidshare.com/files/142269334/JW-Med_Micro.chm

project 10 to the 100

Project 10100

Submission Deadline:
October 20th, 2008

Have a great idea for helping a lot of people? Submit it

click here to submit